Translational science is defined as a process to apply discoveries of laboratories and preclinical studies to human studies in order to improve patients’ care, population health, and public policy outcomes. Application is expanding, including translational pain science.
Neural and hormonal pathways play roles in the complex pain transmission (Watkins and Mayer 1982). Cancer induced bone pain and neuropathic pains remain as clinical challenges.
In this regard, translational pain research is bridging mechanism bases of neuroscience at molecular levels to human studies (Kruger and Light eds. 2010).
Such translation necessitates complex processes of governance and ethics. Thus, social sciences play a significant role in science organizations.
Regarding social science approaches to science organizations, see:
Azoulay, P. (2004), Capturing Knowledge within and across Firm Boundaries: Evidence from Clinical Development, The American Economic Review, 94(5).
Elhauge, E. ed. (2010), The Fragmentation of U.S. Health Care, Oxford University Press.
Rangan, S. et a. (2006), Constructive Partnerships: When Alliances between Private Firms and Public Actors can Enable Creative Strategies, Academy of Management Review, 31(3): 735-751.
Short, J. and M. W. Toffel (2010), Making Self-Regulation More Than Merely Symbolic: The Critical Role of the Legal Environment, Administrative Science Quarterly 55.
Vaughn, D. (1990), Autonomy, Independence, and Social Control: NASA and the Space Shuttle Challenger, Administrative Science Quarterly, 35. Cf. NASA ended the Space Shuttle Program successfully in 2011.
Our missions are to:
1. Conduct policy-oriented research on mechanisms that will advance paths towards individualizing cancer therapeutics and diagnostics, especially for metastasized/ rare cancers; and